Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads
Replication of eukaryotic genomes is highly stochastic, making it difficult to determine the replication dynamics of individual molecules with existing methods. We report a sequencing method for the measurement of replication fork movement on single molecules by detecting nucleotide analog signal cu...
Asıl Yazarlar: | Müller, C, Boemo, M, Spingardi, P, Kessler, B, Kriaucionis, S, Simpson, J, Nieduszynski, C |
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Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
Springer Nature
2019
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