Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads

Replication of eukaryotic genomes is highly stochastic, making it difficult to determine the replication dynamics of individual molecules with existing methods. We report a sequencing method for the measurement of replication fork movement on single molecules by detecting nucleotide analog signal cu...

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Detaylı Bibliyografya
Asıl Yazarlar: Müller, C, Boemo, M, Spingardi, P, Kessler, B, Kriaucionis, S, Simpson, J, Nieduszynski, C
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Springer Nature 2019

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