RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

Cell plasticity is a crucial hallmark leading to cancer metastasis. Upregulation of Rho/ROCK pathway drives actomyosin contractility, protrusive forces, and contributes to the occurrence of highly invasive amoeboid cells in tumors. Cancer stem cells are similarly associated with metastasis, but how...

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Bibliographic Details
Main Authors:	Tognoli, ML, Vlahov, N, Steenbeek, S, Grawenda, AM, Eyres, M, Cano-Rodriguez, D, Scrace, S, Kartsonaki, C, von Kriegsheim, A, Willms, E, Wood, MJ, O'Neill, E, Rots, MG, van Rheenen, J, Pankova, D
Format:	Journal article
Language:	English
Published:	EMBO Press 2021

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