RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

Cell plasticity is a crucial hallmark leading to cancer metastasis. Upregulation of Rho/ROCK pathway drives actomyosin contractility, protrusive forces, and contributes to the occurrence of highly invasive amoeboid cells in tumors. Cancer stem cells are similarly associated with metastasis, but how...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Tognoli, ML, Vlahov, N, Steenbeek, S, Grawenda, AM, Eyres, M, Cano-Rodriguez, D, Scrace, S, Kartsonaki, C, von Kriegsheim, A, Willms, E, Wood, MJ, O'Neill, E, Rots, MG, van Rheenen, J, Pankova, D
Format: Journal article
Sprache:English
Veröffentlicht: EMBO Press 2021

Ähnliche Einträge

Ähnliche Einträge