Microparticle association and heterogeneity of tumor-derived tissue factor in plasma: is it important for coagulation activation?

BACKGROUND: Tumor-derived tissue factor (TF) activates coagulation in vitro and in vivo in an orthotopic model of human pancreatic cancer. Here, we further characterized tumor-derived TF in this model. METHODS: Conditioned medium (CM) of L3.6pl human pancreatic tumor cells and plasma from nude mice...

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Main Authors: Davila, M, Robles-Carrillo, L, Unruh, D, Huo, Q, Gardiner, C, Sargent, I, Adam, M, Woodhams, B, Francis, J, Bogdanov, V, Amirkhosravi, A
格式: Journal article
语言:English
出版: 2014