Genomic analysis of local variation and recent evolution in Plasmodium vivax

The widespread distribution and relapsing nature of Plasmodium vivax infection present major challenges for malaria elimination. To characterise the genetic diversity of this parasite within individual infections and across the population, we performed deep genome sequencing of >200 clinical...

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Main Authors: Kwiatkowski, D, Pearson, R, Amato, R, Auburn, S, Miotto, O, Almagro-Garcia, J, Amaratunga, C, Suon, S, Noviyanti, R, Trimarsanto, H, Marfurt, J, Anstey, N, William, T, Boni, M, Dolecek, C, Tinh Tran, H, White, N, Michon, P, Siba, P, Tavul, L, Harrison, G, Barry, A, Mueller, I, Ferreira, M, Karunaweera, N, Randrianarivelojosia, M, Gao, Q, Hubbart, C, Hart, L, Jeffery, B, Drury, E, Mead, D, Kekre, M, Campino, S, Manske, M, Cornelius, V, Macinnis, B, Rockett, K, Miles, A, Rayner, J, Fairhurst, R, Nosten, F, Price, R
格式: Journal article
出版: Nature Publishing Group 2016