T₂-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS.

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)(G93A) transgenic mouse model of ALS offers a unique opportunity to study and potentially manipulate presymptomatic patho...

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Bibliographic Details
Main Authors: Evans, M, Serres, S, Khrapitchev, A, Stolp, H, Anthony, D, Talbot, K, Turner, M, Sibson, N
Format: Journal article
Language:English
Published: 2014