Targeting prolyl-tRNA synthetase to accelerate drug discovery against malaria, leishmaniasis, toxoplasmosis, cryptosporidiosis, and coccidiosis.

Eitemau Tebyg

• Structure of prolyl-tRNA synthetase-halofuginone complex provides basis for development of drugs against malaria and toxoplasmosis
  gan: Jain, V, et al.
  Cyhoeddwyd: (2015)
• Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis
  gan: Manickam Yogavel, et al.
  Cyhoeddwyd: (2023-02-01)
• Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis.
  gan: Manickam Yogavel, et al.
  Cyhoeddwyd: (2023-02-01)
• ATP mimetics targeting prolyl-tRNA synthetases as a new avenue for antimalarial drug development
  gan: Siddhartha Mishra, et al.
  Cyhoeddwyd: (2024-07-01)
• Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development.
  gan: Yogavel Manickam, et al.
  Cyhoeddwyd: (2022-03-01)