The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway.

The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway.

The Menkes disease gene encodes a P-type transmembrane ATPase (ATP7A) that translocates cytosolic copper ions across intracellular membranes of compartments along the secretory pathway. ATP7A moves from the trans-Golgi network (TGN) to the cell surface in response to exogenously added copper ions an...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Cobbold, C, Coventry, J, Ponnambalam, S, Monaco, A
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2003

Eitemau Tebyg

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