The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway.

The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway.

The Menkes disease gene encodes a P-type transmembrane ATPase (ATP7A) that translocates cytosolic copper ions across intracellular membranes of compartments along the secretory pathway. ATP7A moves from the trans-Golgi network (TGN) to the cell surface in response to exogenously added copper ions an...

Bibliografiset tiedot
Päätekijät:	Cobbold, C, Coventry, J, Ponnambalam, S, Monaco, A
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2003

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