Novel display of knotted DNA molecules by two-dimensional gel electrophoresis.

We describe a two-dimensional agarose gel electrophoresis procedure that improves the resolution of knotted DNA molecules. The first gel dimension is run at low voltage, and DNA knots migrate according to their compactness. The second gel dimension is run at high voltage, and DNA knots migrate accor...

詳細記述

書誌詳細
主要な著者: Trigueros, S, Arsuaga, J, Vazquez, M, Sumners, D, Roca, J
フォーマット: Journal article
言語:English
出版事項: 2001