Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia

Proteomic profiling reveals ACSS2 facilitating metabolic support in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by genomic aberrations in oncogenes, cytogenetic abnormalities, and an aberrant epigenetic landscape. Nearly 50% of AML cases will relapse with current treatment. A major source of therapy resistance is the interaction of mesenchy...

Full description

Bibliographic Details
Main Authors: Mochmann, LH, Treue, D, Bockmayr, M, Silva, P, Zasada, C, Mastrobuoni, G, Bayram, S, Forbes, M, Jurmeister, P, Liebig, S, Blau, O, Schleich, K, Splettstoesser, B, Nordmann, TM, von der Heide, EK, Isaakidis, K, Schulze, V, Busch, C, Siddiq, H, Schlee, C, Hester, S, Fransecky, L, Neumann, M, Kempa, S
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2024

Similar Items