A STEREOCONTROLLED APPROACH TO 1-BETA-METHYLCARBAPENEM

Conjugate addition of lithium N-allyl-N-α-methylbenzylamide to chiral α,β-unsaturated esters is subject to double stereodifferentiation, the mismatched pair reaction allowing access to an intermediate for 1β-methylcarbapenem synthesis. © 1995.

Dettagli Bibliografici
Autori principali: Davies, S, Hedgecock, C, Mckenna, J
Natura: Journal article
Lingua:English
Pubblicazione: 1995
Descrizione
Riassunto:Conjugate addition of lithium N-allyl-N-α-methylbenzylamide to chiral α,β-unsaturated esters is subject to double stereodifferentiation, the mismatched pair reaction allowing access to an intermediate for 1β-methylcarbapenem synthesis. © 1995.