Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.

The gene for insulin-degrading enzyme (IDE) represents a strong positional and biological candidate for type 2 diabetes susceptibility. IDE maps to chromosome 10q23.3, a region linked to diabetes in several populations; the rat homolog has been directly implicated in diabetes susceptibility; and kno...

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Detalhes bibliográficos
Main Authors: Groves, C, Wiltshire, S, Smedley, D, Owen, K, Frayling, T, Walker, M, Hitman, G, Levy, J, O'Rahilly, S, Menzel, S, Hattersley, A, McCarthy, M
Formato: Journal article
Idioma:English
Publicado em: 2003