Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.

Míreanna comhchosúla

• Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.
  de réir: Wiltshire, S, et al.
  Foilsithe / Cruthaithe: (2002)
• Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.
  de réir: Groves, C, et al.
  Foilsithe / Cruthaithe: (2006)
• No evidence for linkage at candidate type 2 diabetes susceptibility loci on chromosomes 12 and 20 in United Kingdom Caucasians.
  de réir: Frayling, T, et al.
  Foilsithe / Cruthaithe: (2000)
• Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.
  de réir: Liew, C, et al.
  Foilsithe / Cruthaithe: (2004)
• Linkage analysis in the Diabetes (UK) Warren 2 sibpair repository supports localisation of a type 2 diabetes susceptibility gene to chromosome 1q21-24.
  de réir: McCarthy, M, et al.
  Foilsithe / Cruthaithe: (2001)