Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.

Viral hepatitis is a major public health threat and a leading cause of death worldwide. Annual mortality from viral hepatitis is similar to that of other major infectious diseases such as HIV and tuberculosis. Highly effective prevention measures and treatments have made the global elimination of vi...

Full description

Bibliographic Details
Main Authors: Cooke, GS, Andrieux-Meyer, I, Applegate, TL, Atun, R, Burry, JR, Cheinquer, H, Dusheiko, G, Feld, JJ, Gore, C, Griswold, MG, Hamid, S, Hellard, ME, Hou, J, Howell, J, Jia, J, Kravchenko, N, Lazarus, JV, Lemoine, M, Lesi, OA, Maistat, L, McMahon, BJ, Razavi, H, Roberts, T, Simmons, B, Sonderup, MW, Spearman, CW, Taylor, BE, Thomas, DL, Waked, I, Ward, JW, Wiktor, SZ, Lancet Gastroenterology and Hepatology Commissioners, Barnes, E
Format: Journal article
Language:English
Published: Elsevier 2019
_version_ 1797085066079240192
author Cooke, GS
Andrieux-Meyer, I
Applegate, TL
Atun, R
Burry, JR
Cheinquer, H
Dusheiko, G
Feld, JJ
Gore, C
Griswold, MG
Hamid, S
Hellard, ME
Hou, J
Howell, J
Jia, J
Kravchenko, N
Lazarus, JV
Lemoine, M
Lesi, OA
Maistat, L
McMahon, BJ
Razavi, H
Roberts, T
Simmons, B
Sonderup, MW
Spearman, CW
Taylor, BE
Thomas, DL
Waked, I
Ward, JW
Wiktor, SZ
Lancet Gastroenterology and Hepatology Commissioners
Barnes, E
author_facet Cooke, GS
Andrieux-Meyer, I
Applegate, TL
Atun, R
Burry, JR
Cheinquer, H
Dusheiko, G
Feld, JJ
Gore, C
Griswold, MG
Hamid, S
Hellard, ME
Hou, J
Howell, J
Jia, J
Kravchenko, N
Lazarus, JV
Lemoine, M
Lesi, OA
Maistat, L
McMahon, BJ
Razavi, H
Roberts, T
Simmons, B
Sonderup, MW
Spearman, CW
Taylor, BE
Thomas, DL
Waked, I
Ward, JW
Wiktor, SZ
Lancet Gastroenterology and Hepatology Commissioners
Barnes, E
author_sort Cooke, GS
collection OXFORD
description Viral hepatitis is a major public health threat and a leading cause of death worldwide. Annual mortality from viral hepatitis is similar to that of other major infectious diseases such as HIV and tuberculosis. Highly effective prevention measures and treatments have made the global elimination of viral hepatitis a realistic goal, endorsed by all WHO member states. Ambitious targets call for a global reduction in hepatitis-related mortality of 65% and a 90% reduction in new infections by 2030. This Commission draws together a wide range of expertise to appraise the current global situation and to identify priorities globally, regionally, and nationally needed to accelerate progress. We identify 20 heavily burdened countries that account for over 75% of the global burden of viral hepatitis. Key recommendations include a greater focus on national progress towards elimination with support given, if necessary, through innovative financing measures to ensure elimination programmes are fully funded by 2020. In addition to further measures to improve access to vaccination and treatment, greater attention needs to be paid to access to affordable, high-quality diagnostics if testing is to reach the levels needed to achieve elimination goals. Simplified, decentralised models of care removing requirements for specialised prescribing will be required to reach those in need, together with sustained efforts to tackle stigma and discrimination. We identify key examples of the progress that has already been made in many countries throughout the world, demonstrating that sustained and coordinated efforts can be successful in achieving the WHO elimination goals.
first_indexed 2024-03-07T02:03:52Z
format Journal article
id oxford-uuid:9e4bae77-4ecf-4cdb-b494-7fdbb5f26a83
institution University of Oxford
language English
last_indexed 2024-03-07T02:03:52Z
publishDate 2019
publisher Elsevier
record_format dspace
spelling oxford-uuid:9e4bae77-4ecf-4cdb-b494-7fdbb5f26a832022-03-27T00:49:10ZAccelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9e4bae77-4ecf-4cdb-b494-7fdbb5f26a83EnglishSymplectic Elements at OxfordElsevier2019Cooke, GSAndrieux-Meyer, IApplegate, TLAtun, RBurry, JRCheinquer, HDusheiko, GFeld, JJGore, CGriswold, MGHamid, SHellard, MEHou, JHowell, JJia, JKravchenko, NLazarus, JVLemoine, MLesi, OAMaistat, LMcMahon, BJRazavi, HRoberts, TSimmons, BSonderup, MWSpearman, CWTaylor, BEThomas, DLWaked, IWard, JWWiktor, SZLancet Gastroenterology and Hepatology CommissionersBarnes, EViral hepatitis is a major public health threat and a leading cause of death worldwide. Annual mortality from viral hepatitis is similar to that of other major infectious diseases such as HIV and tuberculosis. Highly effective prevention measures and treatments have made the global elimination of viral hepatitis a realistic goal, endorsed by all WHO member states. Ambitious targets call for a global reduction in hepatitis-related mortality of 65% and a 90% reduction in new infections by 2030. This Commission draws together a wide range of expertise to appraise the current global situation and to identify priorities globally, regionally, and nationally needed to accelerate progress. We identify 20 heavily burdened countries that account for over 75% of the global burden of viral hepatitis. Key recommendations include a greater focus on national progress towards elimination with support given, if necessary, through innovative financing measures to ensure elimination programmes are fully funded by 2020. In addition to further measures to improve access to vaccination and treatment, greater attention needs to be paid to access to affordable, high-quality diagnostics if testing is to reach the levels needed to achieve elimination goals. Simplified, decentralised models of care removing requirements for specialised prescribing will be required to reach those in need, together with sustained efforts to tackle stigma and discrimination. We identify key examples of the progress that has already been made in many countries throughout the world, demonstrating that sustained and coordinated efforts can be successful in achieving the WHO elimination goals.
spellingShingle Cooke, GS
Andrieux-Meyer, I
Applegate, TL
Atun, R
Burry, JR
Cheinquer, H
Dusheiko, G
Feld, JJ
Gore, C
Griswold, MG
Hamid, S
Hellard, ME
Hou, J
Howell, J
Jia, J
Kravchenko, N
Lazarus, JV
Lemoine, M
Lesi, OA
Maistat, L
McMahon, BJ
Razavi, H
Roberts, T
Simmons, B
Sonderup, MW
Spearman, CW
Taylor, BE
Thomas, DL
Waked, I
Ward, JW
Wiktor, SZ
Lancet Gastroenterology and Hepatology Commissioners
Barnes, E
Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title_full Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title_fullStr Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title_full_unstemmed Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title_short Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission.
title_sort accelerating the elimination of viral hepatitis a lancet gastroenterology amp hepatology commission
work_keys_str_mv AT cookegs acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT andrieuxmeyeri acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT applegatetl acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT atunr acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT burryjr acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT cheinquerh acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT dusheikog acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT feldjj acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT gorec acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT griswoldmg acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT hamids acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT hellardme acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT houj acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT howellj acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT jiaj acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT kravchenkon acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT lazarusjv acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT lemoinem acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT lesioa acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT maistatl acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT mcmahonbj acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT razavih acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT robertst acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT simmonsb acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT sonderupmw acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT spearmancw acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT taylorbe acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT thomasdl acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT wakedi acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT wardjw acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT wiktorsz acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT lancetgastroenterologyandhepatologycommissioners acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission
AT barnese acceleratingtheeliminationofviralhepatitisalancetgastroenterologyamphepatologycommission