Fibroblast growth factor receptor 2, gain-of-function mutations, and tumourigenesis: investigating a potential link.

Activating germline mutations in the fibroblast growth factor receptor (FGFR) gene family have been identified in several dominantly inherited skeletal disorders; in the case of FGFR3, the same somatically arising mutations have also been isolated from a variety of tumour tissues. Whilst the role of...

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Bibliographic Details
Main Authors: Hansen, R, Goriely, A, Wall, SA, Roberts, I, Wilkie, A
Format: Journal article
Language:English
Published: 2005