Fibroblast growth factor receptor 2, gain-of-function mutations, and tumourigenesis: investigating a potential link.
Activating germline mutations in the fibroblast growth factor receptor (FGFR) gene family have been identified in several dominantly inherited skeletal disorders; in the case of FGFR3, the same somatically arising mutations have also been isolated from a variety of tumour tissues. Whilst the role of...
Main Authors: | Hansen, R, Goriely, A, Wall, SA, Roberts, I, Wilkie, A |
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Format: | Journal article |
Language: | English |
Published: |
2005
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