Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1).

Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1).

COX-2 (cyclo-oxygenase-2) mRNA is degraded rapidly in resting cells, but is stabilized by the mitogen-activated protein kinase p38 signalling pathway in response to pro-inflammatory stimuli. A conserved ARE (AU-rich element) of the COX-2 3' untranslated region, CR1 (conserved region 1), acts as...

Bibliográfalaš dieđut
Váldodahkkit:	Sully, G, Dean, J, Wait, R, Rawlinson, L, Santalucia, T, Saklatvala, J, Clark, A
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2004

Geahča maid

Identification of a novel AU-rich-element-binding protein which is related to AUF1
Dahkki: Dean, J, et al.
Almmustuhtton: (2002)

Identification of a novel AU-rich-element-binding protein which is related to AUF1.
Dahkki: Dean, J, et al.
Almmustuhtton: (2002)

AUF1 and HuR: possible implications of mRNA stability in thyroid function and disorders
Dahkki: Trojanowicz Bogusz, et al.
Almmustuhtton: (2011-08-01)

RNA binding protein HuR regulates the expression of ABCA1[S]
Dahkki: Cristina M. Ramírez, et al.
Almmustuhtton: (2014-06-01)

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.
Dahkki: Kawaljit Kaur, et al.
Almmustuhtton: (2017-01-01)

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.
Dahkki: Christopher Tiedje, et al.
Almmustuhtton: (2012-09-01)

HuR binding to AU-rich elements present in the 3' untranslated region of <it>Classical swine fever virus</it>
Dahkki: Huang Chin-Cheng, et al.
Almmustuhtton: (2011-07-01)

An HuR mutant, HuR-V225I, identified in adult T-cell Leukemia/Lymphoma, alters the pro-apoptotic function of HuR
Dahkki: Bianca Colalillo, et al.
Almmustuhtton: (2024-12-01)

The RNA-binding protein HuR is a negative regulator in adipogenesis
Dahkki: Diana Teh Chee Siang, et al.
Almmustuhtton: (2020-01-01)

RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
Dahkki: Erica J Hutchins, et al.
Almmustuhtton: (2022-10-01)

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
Dahkki: Feng Yang, et al.
Almmustuhtton: (2019-11-01)

The RNA-binding protein HuR is required for maintenance of the germinal centre response
Dahkki: Ines C. Osma-Garcia, et al.
Almmustuhtton: (2021-11-01)

Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
Dahkki: Feng Yang, et al.
Almmustuhtton: (2023-09-01)

PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
Dahkki: Yueshuang Ke, et al.
Almmustuhtton: (2017-03-01)

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.
Dahkki: Dean, J, et al.
Almmustuhtton: (2001)

Towards the Modulation of RNA-Binding Proteins: New Compounds Targeting Protein HuR
Dahkki: Serena Della Volpe, et al.
Almmustuhtton: (2019-08-01)

Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis
Dahkki: Zhimin Huang, et al.
Almmustuhtton: (2023-06-01)

Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation
Dahkki: Eleni Christodoulou-Vafeiadou, et al.
Almmustuhtton: (2018-11-01)

The Role of RNA-Binding Protein HuR in Lung Cancer by RNA Sequencing Analysis
Dahkki: Xiong Ye, et al.
Almmustuhtton: (2022-04-01)

Analysis of the kinetic of expression of tristetraprolin and HuR by rheumatoid arthritis patients pheripheral blood mononuclear cells stimulated with lipopolysaccharide
Dahkki: M. Fabris, et al.
Almmustuhtton: (2004-06-01)

Niclosamide improves cancer immunotherapy by modulating RNA-binding protein HuR-mediated PD-L1 signaling
Dahkki: Qi Zhang, et al.
Almmustuhtton: (2023-10-01)

Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
Dahkki: Yueshuang Ke, et al.
Almmustuhtton: (2017-03-01)

HuR controls glutaminase RNA metabolism
Dahkki: Douglas Adamoski, et al.
Almmustuhtton: (2024-07-01)

ADORA2A-AS1 Restricts Hepatocellular Carcinoma Progression via Binding HuR and Repressing FSCN1/AKT Axis
Dahkki: Jian Pu, et al.
Almmustuhtton: (2021-10-01)

Deficiency of the RNA-binding protein ELAVL1/HuR leads to the failure of endogenous and exogenous neuroprotection of retinal ganglion cells
Dahkki: Anna Pacwa, et al.
Almmustuhtton: (2023-02-01)

Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis
Dahkki: Yuhan Wang, et al.
Almmustuhtton: (2019-12-01)

S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD
Dahkki: Tao Guo, et al.
Almmustuhtton: (2021-03-01)

Discriminating between HuR and TTP binding sites using the k-spectrum kernel method.
Dahkki: Shweta Bhandare, et al.
Almmustuhtton: (2017-01-01)

MiR-200c and HuR in ovarian cancer
Dahkki: Prislei Silvia, et al.
Almmustuhtton: (2013-02-01)

Investigating the roles of HuR during wound healing
Dahkki: Quah, Clarissa Bernice
Almmustuhtton: (2020)

Regulation of HuR by DNA Damage Response Kinases
Dahkki: Hyeon Ho Kim, et al.
Almmustuhtton: (2010-01-01)

Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR
Dahkki: Aixin Yu, et al.
Almmustuhtton: (2025-01-01)

Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer
Dahkki: Tingjia Zhu, et al.
Almmustuhtton: (2022-05-01)

The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro
Dahkki: Gronenborn Angela M, et al.
Almmustuhtton: (2010-05-01)

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR (vol 21, pg 721, 2001)
Dahkki: Dean, J, et al.
Almmustuhtton: (2005)

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage
Dahkki: Dai, Weijun, et al.
Almmustuhtton: (2013)

RNA-binding protein HuR reprograms immune T cells and promotes oral squamous cell carcinoma
Dahkki: Mrinmoyee Majumder, et al.
Almmustuhtton: (2024-06-01)

Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy
Dahkki: Lanjing Wei, et al.
Almmustuhtton: (2023-10-01)

Triciribine Engages ZFP36L1 and HuR to Stabilize LDLR mRNA
Dahkki: Hilde Sundvold
Almmustuhtton: (2020-10-01)

HuR modulation counteracts lipopolysaccharide response in murine macrophages
Dahkki: Isabelle Bonomo, et al.
Almmustuhtton: (2023-03-01)