Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.
Antigen presentation by major histocompatibility complex class II molecules is essential for antibody production and T cell activation. For most class II alleles, peptide binding depends on the catalytic action of human histocompatibility leukocyte antigens (HLA)-DM. HLA-DO is selectively expressed...
Main Authors: | van Ham, M, van Lith, M, Lillemeier, B, Tjin, E, Grüneberg, U, Rahman, D, Pastoors, L, van Meijgaarden, K, Roucard, C, Trowsdale, J, Ottenhoff, T, Pappin, D, Neefjes, J |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2000
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