Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.

Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO.

Antigen presentation by major histocompatibility complex class II molecules is essential for antibody production and T cell activation. For most class II alleles, peptide binding depends on the catalytic action of human histocompatibility leukocyte antigens (HLA)-DM. HLA-DO is selectively expressed...

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Bibliographic Details
Main Authors: van Ham, M, van Lith, M, Lillemeier, B, Tjin, E, Grüneberg, U, Rahman, D, Pastoors, L, van Meijgaarden, K, Roucard, C, Trowsdale, J, Ottenhoff, T, Pappin, D, Neefjes, J
Format: Journal article
Language:English
Published: 2000

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