Hypoxia-inducible factor-2 is a novel regulator of aberrant CXCL12 expression in multiple myeloma plasma cells.
BACKGROUND: Multiple myeloma is an incurable malignancy of bone marrow plasma cells. Progression of multiple myeloma is accompanied by an increase in bone marrow angiogenesis. Studies from our laboratory suggest a role for the CXCL12 chemokine in this process, with circulating levels of CXCL12 corr...
Κύριοι συγγραφείς: | , , , , , , , , |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2010
|