Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss.

Analysis of the mouse mutant Cloth-ears shows a role for the voltage-gated sodium channel Scn8a in peripheral neural hearing loss.

Deafness is the most common sensory disorder in humans and the aetiology of genetic deafness is complex. Mouse mutants have been crucial in identifying genes involved in hearing. However, many deafness genes remain unidentified. Using N-ethyl N-nitrosourea (ENU) mutagenesis to generate new mouse mod...

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Bibliographic Details
Main Authors: Mackenzie, F, Parker, A, Parkinson, N, Oliver, P, Brooker, D, Underhill, P, Lukashkina, V, Lukashkin, A, Holmes, C, Brown, S
Format: Journal article
Language:English
Published: 2009

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