5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with [125I]SB-258585.

The 5-hydroxytryptamine (5-HT; serotonin)-6 receptor (5-HT6R) is a putative target of atypical antipsychotic drugs and its mRNA expression is altered in schizophrenia. [125I]SB-258585 is a selective 5-HT6R antagonist which has been well characterized for use in the rat brain. The present study evalu...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: East, S, Burnet, P, Leslie, R, Roberts, J, Harrison, P
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2002