The energetics of transmembrane helix insertion into a lipid bilayer.

Free energy profiles for insertion of a hydrophobic transmembrane protein α-helix (M2 from CFTR) into a lipid bilayer have been calculated using coarse-grained molecular dynamics simulations and umbrella sampling to yield potentials of mean force along a reaction path corresponding to translation of...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Chetwynd, A, Wee, C, Hall, B, Sansom, MS
פורמט: Journal article
שפה:English
יצא לאור: 2010

פריטים דומים