Interactions of hydrolyzed β-lactams with the L1 metallo-β-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products

<p>L1 is a dizinc subclass B3 metallo-&beta;-lactamase (MBL) that hydrolyzes most &beta;-lactam antibiotics and is a key resistance determinant in the Gram-negative pathogen&nbsp;<em>Stenotrophomonas maltophilia</em>, an important cause of nosocomial infections in immun...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Hinchliffe, P, Calvopiña, K, Rabe, P, Mojica, MF, Schofield, CJ, Dmitrienko, GI, Bonomo, RA, Vila, AJ, Spencer, J
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Elsevier 2023