Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.

We have analyzed the presentation of human histocompatability leukocyte antigen-A*0201-associated tumor peptide antigen MAGE-3271-279 by melanoma cells. We show that specific cytotoxic T lymphocyte (CTL)-recognizing cells transfected with a minigene encoding the preprocessed fragment MAGE-3271-279 f...

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Bibliografski detalji
Glavni autori: Valmori, D, Gileadi, U, Servis, C, Dunbar, P, Cerottini, J, Romero, P, Cerundolo, V, Lévy, F
Format: Journal article
Jezik:English
Izdano: 1999