APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model.

APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model.

BACKGROUND: The APOE genotype predicts the age at onset of Alzheimer disease (AD) and neuropathologic progression. However, studies relating APOE alleles to the rate of cognitive decline have been inconclusive. This may stem from their use of linear statistical analyses. OBJECTIVE: To model relation...

Full description

Bibliographic Details
Main Authors:	Martins, C, Oulhaj, A, de Jager, C, Williams, J
Format:	Journal article
Language:	English
Published:	2005

Similar Items

Homocysteine as a predictor of cognitive decline in Alzheimer's disease
by: Oulhaj, A, et al.
Published: (2010)

Homocysteine as a predictor of cognitive decline in Alzheimer's disease.
by: Oulhaj, A, et al.
Published: (2010)

Interaction between <i>KLOTHO</i>-VS Heterozygosity and <i>APOE</i> ε4 Allele Predicts Rate of Cognitive Decline in Late-Onset Alzheimer’s Disease
by: Xi Richard Chen, et al.
Published: (2023-04-01)

Cognitive declines precede and predict functional declines in aging and Alzheimer's disease.
by: Laura B Zahodne, et al.
Published: (2013-01-01)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
by: B.V.P. de-Almada, et al.
Published: (2012-01-01)

Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease
by: Kazushi Suzuki, et al.
Published: (2020-01-01)

Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment
by: Oulhaj, A, et al.
Published: (2016)

Protective effect of the APOE-e3 allele in Alzheimer’s disease
by: B.V.P. de-Almada, et al.
Published: (2012-01-01)

Predictive Factors of Rapid Cognitive Decline in Patients with Alzheimer Disease
by: Coralie Barbe, et al.
Published: (2016-12-01)

Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation.
by: Holmes, C, et al.
Published: (2005)

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score
by: Jori Tomassen, et al.
Published: (2022-12-01)

Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease
by: Céline H. De Jager, et al.
Published: (2021-02-01)

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
by: Allen, G, et al.
Published: (2016)

Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment
by: Pia Kivisäkk, et al.
Published: (2023-03-01)

Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease
by: Hákon Valur Dansson, et al.
Published: (2021-09-01)

Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease.
by: Lai, M, et al.
Published: (2002)

APOE GENE POLYMORPHISM: THE IMPACT OF APOE4 ALLELE ON SYSTEMIC INFLAMMATION AND ITS ROLE IN THE PATHOGENESIS OF ALZHEIMER’S DISEASE
by: I. K. Malashenkova, et al.
Published: (2018-06-01)

A TOMM40/APOE allele encoding APOE‐E3 predicts high likelihood of late‐onset Alzheimer’s disease in autopsy cases
by: Selma M. Soyal, et al.
Published: (2020-08-01)

MRI Markers of Small Vessel Disease and the APOE Allele in Cognitive Impairment
by: Mana Shams, et al.
Published: (2022-07-01)

Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.
by: Lai, M, et al.
Published: (2006)

APOE epsilon 4 allele affects presynaptic, but not postsynaptic cholinergic markers in Alzheimer's disease neocortex
by: Lai, M, et al.
Published: (2006)

Predicting cognitive decline in healthy older adults.
by: De Jager, C, et al.
Published: (2005)

PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients.
by: Belbin, O, et al.
Published: (2009)

Blood Neurofilament Levels Predict Cognitive Decline across the Alzheimer’s Disease Continuum
by: Sylvain Lehmann, et al.
Published: (2023-12-01)

Effect of APOE and CD33 on Cognitive Decline.
by: Kathleen M Hayden, et al.
Published: (2015-01-01)

Impact of atrial fibrillation on the cognitive decline in Alzheimer’s disease
by: Taizen Nakase, et al.
Published: (2023-01-01)

APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer's Disease.
by: Timothy J Hohman, et al.
Published: (2017-01-01)

Metabolic syndrome biomarkers relate to rate of cognitive decline in MCI and dementia stages of Alzheimer’s disease
by: Jagan A. Pillai, et al.
Published: (2023-03-01)

Multimodal Discrimination between Normal Aging, Mild Cognitive Impairment and Alzheimer’s Disease and Prediction of Cognitive Decline
by: Corinna M. Bauer, et al.
Published: (2018-02-01)

Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer’s disease
by: Jagan A. Pillai, et al.
Published: (2020-07-01)

Structural Network Efficiency Predicts Resilience to Cognitive Decline in Elderly at Risk for Alzheimer’s Disease
by: Florian U. Fischer, et al.
Published: (2021-02-01)

Correction: Effect of APOE and CD33 on Cognitive Decline.
by: Kathleen M Hayden, et al.
Published: (2015-01-01)

Interactions Between Neuropsychiatric Symptoms and Alzheimer's Disease Neuroimaging Biomarkers in Predicting Longitudinal Cognitive Decline
by: Anna Pink, et al.
Published: (2023-03-01)

Levels of CSF prostaglandin E2, cognitive decline, and survival in Alzheimer's disease.
by: Combrinck, M, et al.
Published: (2006)

Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE ε4 allele, in relation to cognitive function and cerebral glucose metabolism
by: T. Darreh-Shori, et al.
Published: (2006-11-01)

Air pollution is associated with faster cognitive decline in Alzheimer's disease
by: Young‐gun Lee, et al.
Published: (2023-06-01)

Traditional used Plants against Cognitive Decline and Alzheimer Disease
by: Gunter Peter Eckert
Published: (2010-12-01)

Subjective cognitive decline: The first clinical manifestation of Alzheimer's disease?
by: Adalberto Studart Neto, et al.

Repurposing verapamil for prevention of cognitive decline in sporadic Alzheimer’s disease
by: Heba A Ahmed, et al.
Published: (2022-01-01)

The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease.
by: Ahmed, A, et al.
Published: (1999)