A novel checkpoint mechanism regulating the G1/S transition.
Ultraviolet irradiation of fission yeast cells in G1 phase induced a delay in chromatin binding of replication initiation factors and, consistently, a transient delay in S-phase entry. The cell cycle delay was totally dependent on the Gcn2 kinase, a sensor of the nutritional status, and was accompan...
Päätekijät: | Tvegård, T, Soltani, H, Skjølberg, H, Krohn, M, Nilssen, E, Kearsey, S, Grallert, B, Boye, E |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
2007
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