Solid-state NMR in drug design and discovery for membrane-embedded targets.

Observing drugs and ligands at their site of action in membrane proteins is now possible through the use of a development in biomolecular NMR spectroscopy known as solid-state NMR. Even large, functionally active complexes are being examined using this method, with structural details being resolved...

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Autor principal: Watts, A
Format: Journal article
Idioma:English
Publicat: 2005