A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours

<p>Background: This study evaluated safety, pharmacokinetics, and clinical activity of intravenous and oral rucaparib, a poly (ADP-ribose) polymerase inhibitor, combined with chemotherapy in patients with advanced solid tumours.</p> <p>Methods: Initially, patients received escalati...

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Bibliographic Details
Main Authors: Wilson, R, Jeffry Evans, T, Middleton, M, Molife, L, Spicer, J, Dieras, V, Roxburgh, P, Giordano, H, Jaw-Tsai, S, Goble, S, Plummer, R
Format: Journal article
Published: Cancer Research UK 2017

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