Preparation of Fluorescent Tubulin Binders

Thiocolchicine, taxol and cephalomannine have been used as building blocks for the preparation of four different fluorescent compounds designed to image the tubulin/microtubule network in cells. Thiocolchicine gave the best results and, in particular, the compound derived from conjugation with fluor...

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Bibliographic Details
Main Authors: Riva, E, Mattarella, M, Borrelli, S, Christodoulou, MS, Cartelli, D, Main, M, Faulkner, S, Sykes, D, Cappelletti, G, Snaith, J, Passarella, D
Format: Journal article
Language:English
Published: 2013