Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.

Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.

The crystal structure of the nonclassical human class lb MHC molecule HLA-E has been determined in complex with a prototypic ligand, the nonamer peptide (VMAPRTVLL), derived from the highly conserved residues 3-11 of the human MHC class la leader sequence. The mode of peptide binding retains some of...

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Bibliographic Details
Main Authors:	O'Callaghan, C, Tormo, J, Willcox, B, Braud, V, Jakobsen, B, Stuart, D, Mcmichael, A, Bell, J, Jones, E
Format:	Journal article
Language:	English
Published:	1998

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