Combined single-molecule force and fluorescence measurements for biology.
Recent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes ca...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2003
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| _version_ | 1826288024472780800 |
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| author | Wallace, M Molloy, J Trentham, DR |
| author_facet | Wallace, M Molloy, J Trentham, DR |
| author_sort | Wallace, M |
| collection | OXFORD |
| description | Recent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes can now be studied with nanometer precision and millisecond time resolution. |
| first_indexed | 2024-03-07T02:07:28Z |
| format | Journal article |
| id | oxford-uuid:9f7c2b47-dc4e-449b-959f-2f2cf209c7b3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:07:28Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:9f7c2b47-dc4e-449b-959f-2f2cf209c7b32022-03-27T00:58:05ZCombined single-molecule force and fluorescence measurements for biology.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9f7c2b47-dc4e-449b-959f-2f2cf209c7b3EnglishSymplectic Elements at Oxford2003Wallace, MMolloy, JTrentham, DRRecent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes can now be studied with nanometer precision and millisecond time resolution. |
| spellingShingle | Wallace, M Molloy, J Trentham, DR Combined single-molecule force and fluorescence measurements for biology. |
| title | Combined single-molecule force and fluorescence measurements for biology. |
| title_full | Combined single-molecule force and fluorescence measurements for biology. |
| title_fullStr | Combined single-molecule force and fluorescence measurements for biology. |
| title_full_unstemmed | Combined single-molecule force and fluorescence measurements for biology. |
| title_short | Combined single-molecule force and fluorescence measurements for biology. |
| title_sort | combined single molecule force and fluorescence measurements for biology |
| work_keys_str_mv | AT wallacem combinedsinglemoleculeforceandfluorescencemeasurementsforbiology AT molloyj combinedsinglemoleculeforceandfluorescencemeasurementsforbiology AT trenthamdr combinedsinglemoleculeforceandfluorescencemeasurementsforbiology |