Combined single-molecule force and fluorescence measurements for biology.

Recent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes ca...

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Bibliographic Details
Main Authors: Wallace, M, Molloy, J, Trentham, DR
Format: Journal article
Language:English
Published: 2003