Combined single-molecule force and fluorescence measurements for biology.
Recent advances in single-molecule techniques allow the application of force to an individual biomolecule whilst simultaneously monitoring its response using fluorescent probes. The effects of applied mechanical load on single-enzyme turnovers, biomolecular interactions and conformational changes ca...
Main Authors: | Wallace, M, Molloy, J, Trentham, DR |
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Format: | Journal article |
Language: | English |
Published: |
2003
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