Translocating kilobase RNA through the Staphylococcal α-hemolysin nanopore.

The electrophoretic translocation of polynucleotides through nanopores may permit direct single-molecule nucleic acid sequencing. Here we describe the translocation of ssRNA heteropolymers (91-6083 bases) through the α-hemolysin nanopore. Translocation of these long ssRNAs is characterized by surpri...

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Hlavní autoři: Cracknell, J, Japrung, D, Bayley, H
Médium: Journal article
Jazyk:English
Vydáno: 2013