MAIT cells are enriched in portal tracts and respond to biliary epithelial cells presenting bacterial ligands during liver inflammation

Mucosal-Associated Invariant T (MAIT) cells are unconventional T-cells characterised by the invariant T-cell antigen receptor α-chain, Vα7.2, high expression of CD161 and restriction by the MHC class 1-related molecule, MR1. They are important for antibacterial immunity at mucosal sites; however, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeffery, H, Van Wilgenburg, B, Stirling, K, Parekh, K, Roberts, S, Kurioka, A, Hunter, S, Adams, D, Klenerman, P, Oo, Y
Formato: Conference item
Publicado: Wiley 2015