CD4 T cells can reject major histocompatibility complex class I-incompatible skin grafts.
We have re-investigated the roles of CD4 and CD8 T cell subsets in skin graft rejection across a single class I MHC disparity. Recipient mice were transplanted with skin from donors transgenic for the class I MHC molecule Kb. As expected, CD8 T cells were sufficient for rapid injection; but surprisi...
Main Authors: | Wise, M, Zelenika, D, Bemelman, F, Latinne, D, Bazin, H, Cobbold, S, Waldmann, H |
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Format: | Journal article |
Language: | English |
Published: |
1999
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