Clonal expansion of new penicillin-resistant clade of serogroup W, clonal complex 11 Neisseria meningitidis, Western Australia

In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might af...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Mowlaboccus, S, Jolley, K, Bray, J, Pang, S, Thin Lee, Y, Bew, J, Speers, D, Keil, A, Coombs, G, Kahler, C
التنسيق: Journal article
منشور في: Centers for Disease Control 2017
الوصف
الملخص:In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.