Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project

Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project

Testicular germ cell tumours (TGCT), which comprise seminoma and non-seminoma subtypes, are the most common cancers in young men. In this study, we present a comprehensive whole genome sequencing analysis of adult TGCTs. Leveraging samples from participants recruited via the UK National Health Servi...

書誌詳細
主要な著者:	Ní Leathlobhair, M, Frangou, A, Kinnersley, B, Cornish, AJ, Chubb, D, Lakatos, E, Arumugam, P, Gruber, AJ, Law, P, Tapinos, A, Jakobsdottir, GM, Peneva, I, Sahli, A, Smyth, EM, Ball, RY, Sylva, R, Benes, K, Stark, D, Young, RJ, Lee, ATJ, Wolverson, V, Houlston, RS, Sosinsky, A, Protheroe, A, Wedge, DC, Verrill, C
フォーマット:	Journal article
言語:	English
出版事項:	Nature Research 2024

類似資料

Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project
著者:: Máire Ní Leathlobhair, 等
出版事項: (2024-10-01)

Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology
著者:: Kinnersley, B, 等
出版事項: (2024)

Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
著者:: Culliford, R, 等
出版事項: (2024)

The genomic landscape of 2,023 colorectal cancers
著者:: Cornish, AJ, 等
出版事項: (2024)

The UK’s 100,000 Genomes Project: manifesting policymakers’ expectations
著者:: Gabrielle Natalie Samuel, 等
出版事項: (2017-10-01)

Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project.
著者:: Robbe, P, 等
出版事項: (2018)

Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
著者:: Richard Culliford, 等
出版事項: (2024-07-01)

Understanding experiences of recruiting for, and participating in, genomics research and service transformation: the 100,000 Genomes Project, 2015-17
著者:: Ryan, S, 等
出版事項: (2020)

The 100,000 genomes pilot on rare disease diagnosis in healthcare – a preliminary report
著者:: Smedley, D, 等
出版事項: (2021)

Opportunities and Challenges for Molecular Understanding of Ciliopathies–The 100,000 Genomes Project
著者:: Gabrielle Wheway, 等
出版事項: (2019-03-01)

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
著者:: Zachary R. Chalmers, 等
出版事項: (2017-04-01)

Corrigendum: Opportunities and Challenges for Molecular Understanding of Ciliopathies–The 100,000 Genomes Project
著者:: Gabrielle Wheway, 等
出版事項: (2019-08-01)

BlastFrost: fast querying of 100,000s of bacterial genomes in Bifrost graphs
著者:: Nina Luhmann, 等
出版事項: (2021-01-01)

Prognosis and oncogenomic profiling of patients with tropomyosin receptor kinase fusion cancer in the 100,000 genomes project
著者:: John Bridgewater, 等
出版事項: (2022-01-01)

Increasing the diagnostic yield of childhood glaucoma cases recruited into the 100,000 Genomes Project
著者:: Omayma Al-Saei, 等
出版事項: (2024-05-01)

A systematic analysis of splicing variants identifies new diagnoses in the 100,000 Genomes Project
著者:: Alexander J. M. Blakes, 等
出版事項: (2022-07-01)

A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores
著者:: Moonil Kang, 等
出版事項: (2023-06-01)

Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: recommendations for reporting results
著者:: Magiorkinis, G, 等
出版事項: (2019)

Identification of FH-causing variants in patients with clinical familial hypercholesterolaemia recruited into the 100,000 genome project: preliminary analysis
著者:: A. Rimbert, 等
出版事項: (2021-09-01)

APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types
著者:: G. Maria Jakobsdottir, 等
出版事項: (2022-05-01)

Nanoscopy with more than 100,000 'doughnuts'.
著者:: Chmyrov, A, 等
出版事項: (2013)

Cardiomyopathies in 100,000 genomes project: interval evaluation improves diagnostic yield and informs strategies for ongoing gene discovery
著者:: Katherine S. Josephs, 等
出版事項: (2024-10-01)

Association between tumour somatic mutations and venous thromboembolism in the 100,000 Genomes Project cancer cohort: a study protocol [version 2; peer review: 2 approved]
著者:: Naomi Cornish, 等
出版事項: (2024-12-01)

Edar 100000 topeng muka
著者:: UMP, .
出版事項: (2015)

A signal processing method for alignment-free metagenomic binning: multi-resolution genomic binary patterns
著者:: Kouchaki, S, 等
出版事項: (2019)

Nanoscopy with more than 100,000 'doughnuts'
著者:: Chmyrov, A, 等
出版事項: (2013)

“Not pathogenic until proven otherwise”: perspectives of UK clinical genomics professionals toward secondary findings in context of a Genomic Medicine Multidisciplinary Team and the 100,000 Genomes Project
著者:: Ormondroyd, E, 等
出版事項: (2017)

Using data from the 100,000 Genomes Project to resolve conflicting interpretations of a recurrent TUBB2A mutation
著者:: Ragoussis, V, 等
出版事項: (2021)

The use of biomedical big data for economic analyses of genome sequencing in rare genetic diseases: a case study from the 100,000 Genomes Project
著者:: Fahr, P
出版事項: (2021)

Increased COVID-19 mortality rate in rare disease patients: a retrospective cohort study in participants of the Genomics England 100,000 Genomes project
著者:: Huayu Zhang, 等
出版事項: (2022-04-01)

UPM sasar 100,000 pengunjung
著者:: Utusan Malaysia,
出版事項: (2015)

100,000 warga emas terpinggir
著者:: Utusan Malaysia, Noraini Nordin
出版事項: (2009)

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes
著者:: Ansari-Pour, N, 等
出版事項: (2021)

Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review.
著者:: Broderick, P, 等
出版事項: (2016)

Prognostic determinants in cancer survival: a multidimensional evaluation of clinical and genetic factors across 10 cancer types in the participants of Genomics England’s 100,000 Genomes Project
著者:: Jurgita Gammall, 等
出版事項: (2024-09-01)

Genetic landscape of interval and screen detected breast cancer
著者:: Charlie Mills, 等
出版事項: (2024-05-01)

RM100,000 untuk Cendekia Bitara
著者:: Nur Akhmar, Mohd Abhar
出版事項: (2009)

Huawei latih 100,000 profesional ICT
著者:: Harian Metro,
出版事項: (2012)

Zero to 100,000 : social media tips and tricks for small business /
著者:: 531650 Gratton, Sarah-Jayne, 等
出版事項: (c201)

Protocol and quality assurance for carotid imaging in 100,000 participants of UK Biobank: development and assessment.
著者:: Coffey, S, 等
出版事項: (2017)