The roles of type 2 cytotoxic T cells in inflammation, tissue remodeling, and prostaglandin (PG) D2 production are attenuated by PGD2 receptor 2 antagonism

The roles of type 2 cytotoxic T cells in inflammation, tissue remodeling, and prostaglandin (PG) D2 production are attenuated by PGD2 receptor 2 antagonism

<p>Human type 2 cytotoxic T (Tc2) cells are enriched in severe eosinophilic asthma and can contribute to airway eosinophilia. PGD<sub>2</sub> and its receptor PGD<sub>2</sub> receptor 2 (DP2) play important roles in Tc2 cell activation, including migra...

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Bibliographic Details
Main Authors:	Chen, W, Luo, J, Ye, Y, Hoyle, R, Liu, W, Borst, R, Kazani, S, Shikatani, EA, Erpenbeck, VJ, Pavord, ID, Klenerman, P, Sandham, DA, Xue, L
Format:	Journal article
Language:	English
Published:	American Association of Immunologists 2021

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