An investigation into the structural role of the CCR4-NOT complex in mRNA stability
<p>The CCR4-NOT complex is a global regulator of gene expression which controls mRNA levels by removing the poly-(A) tail, a step known as deadenylation and one that constitutes the rate-limiting step in mRNA decay. The human complex is comprised of eight stably associated CNOT subunits where...
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| Formato: | Thesis |
| Idioma: | English |
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2017
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