An investigation into the structural role of the CCR4-NOT complex in mRNA stability

<p>The CCR4-NOT complex is a global regulator of gene expression which controls mRNA levels by removing the poly-(A) tail, a step known as deadenylation and one that constitutes the rate-limiting step in mRNA decay. The human complex is comprised of eight stably associated CNOT subunits where...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Brazier, H
مؤلفون آخرون: Burgess-Brown, N
التنسيق: أطروحة
اللغة:English
منشور في: 2017
الموضوعات:

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