The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model
Background: Dyskinesia or abnormal involuntary movements (AIMs) are a disabling effect of chronic l-DOPA administration and consequent pulsatile stimulation of dopamine receptors. This abnormal activation causes maladaptive changes including upregulation of FosB expression in dynorphin containing st...
Main Authors: | Thornton, E, Hassall, M, Corrigan, F, Vink, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2014
|
Similar Items
-
Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
by: Cantuti-Castelvetri, Ippolita, et al.
Published: (2011) -
Parkinsonian patients and poor awareness of dyskinesias.
by: Sara ePietracupa, et al.
Published: (2014-03-01) -
Transplantation of melanocytes obtained from the skin ameliorates apomorphine-induced abnormal behavior in rodent hemi-parkinsonian models.
by: Masato Asanuma, et al.
Published: (2013-01-01) -
The beneficial effect of the flavonoid quercetin on behavioral changes in hemi-Parkinsonian rats
by: Mehdi Mehdizadeh, et al.
Published: (2010-01-01) -
The beneficial effect of the flavonoid quercetin on behavioral changes in hemi-Parkinsonian rats
by: Mehdi Mehdizadeh, et al.
Published: (2010-01-01)