The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model

The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model

Background: Dyskinesia or abnormal involuntary movements (AIMs) are a disabling effect of chronic l-DOPA administration and consequent pulsatile stimulation of dopamine receptors. This abnormal activation causes maladaptive changes including upregulation of FosB expression in dynorphin containing st...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Thornton, E, Hassall, M, Corrigan, F, Vink, R
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Elsevier 2014

Παρόμοια τεκμήρια

Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
ανά: Cantuti-Castelvetri, Ippolita, κ.ά.
Έκδοση: (2011)

Parkinsonian patients and poor awareness of dyskinesias.
ανά: Sara ePietracupa, κ.ά.
Έκδοση: (2014-03-01)

Transplantation of melanocytes obtained from the skin ameliorates apomorphine-induced abnormal behavior in rodent hemi-parkinsonian models.
ανά: Masato Asanuma, κ.ά.
Έκδοση: (2013-01-01)

The beneficial effect of the flavonoid quercetin on behavioral changes in hemi-Parkinsonian rats
ανά: Mehdi Mehdizadeh, κ.ά.
Έκδοση: (2010-01-01)

The beneficial effect of the flavonoid quercetin on behavioral changes in hemi-Parkinsonian rats
ανά: Mehdi Mehdizadeh, κ.ά.
Έκδοση: (2010-01-01)

7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate
ανά: M. T. Herrero, κ.ά.
Έκδοση: (2023-05-01)

Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice
ανά: Ziqing Shi, κ.ά.
Έκδοση: (2020-11-01)

Synergistic Effects of Adenosine A2A Antagonist and L-DOPA on Rotational Behaviors in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Mouse Model
ανά: Takahiro Matsuya, κ.ά.
Έκδοση: (2007-01-01)

Prevention of L-Dopa-Induced Dyskinesias by MPEP Blockade of Metabotropic Glutamate Receptor 5 Is Associated with Reduced Inflammation in the Brain of Parkinsonian Monkeys
ανά: Marc Morissette, κ.ά.
Έκδοση: (2022-02-01)

IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
ανά: Romina Aron Badin, κ.ά.
Έκδοση: (2013-01-01)

CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys.
ανά: Boyce, S, κ.ά.
Έκδοση: (1990)

Potential efficacy of nanocurcumin on levodopa-induced dyskinesia in a rat parkinsonian model
ανά: Pegah Ashrafi, κ.ά.
Έκδοση: (2022-11-01)

Substance P and its tachykinin NK1 receptor: a novel neuroprotective target for Parkinson′s disease
ανά: Emma Thornton, κ.ά.
Έκδοση: (2015-01-01)

Correction: IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates
Έκδοση: (2013-01-01)

The adenosine A2A receptor antagonist/inverse agonist, KW-6356 enhances the anti-parkinsonian activity of L-DOPA with a low risk of dyskinesia in MPTP-treated common marmosets
ανά: Yutaro Ohno, κ.ά.
Έκδοση: (2023-07-01)

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats
ανά: Natosha M. Mercado, κ.ά.
Έκδοση: (2024-08-01)

Intensive Rehabilitation Treatment in Parkinsonian Patients with Dyskinesias: A Preliminary Study with 6-Month Followup
ανά: Giuseppe Frazzitta, κ.ά.
Έκδοση: (2012-01-01)

Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats
ανά: Stefania eSgroi, κ.ά.
Έκδοση: (2014-10-01)

Chronic Nasal Administration of Kisspeptin-54 Regulates Mood-Related Disorders Via Amygdaloid GABA in Hemi-Parkinsonian Rats
ανά: Osman Sinen, κ.ά.
Έκδοση: (2024-11-01)

Molecular Insights into the Interaction of Tryptophan Metabolites with the Human Aryl Hydrocarbon Receptor in Silico: Tryptophan as Antagonist and no Direct Involvement of Kynurenine
ανά: Abdulla A-B Badawy, κ.ά.
Έκδοση: (2024-09-01)

NK1-r Antagonist Treatment Comparable to Decompressive Craniectomy in Reducing Intracranial Pressure Following Stroke
ανά: Annabel J. Sorby-Adams, κ.ά.
Έκδοση: (2019-07-01)

AV-101, a Pro-Drug Antagonist at the NMDA Receptor Glycine Site, Reduces L-Dopa Induced Dyskinesias in MPTP Monkeys
ανά: Mélanie Bourque, κ.ά.
Έκδοση: (2022-11-01)

Dynamic Involvement of Striatal NG2-glia in L-DOPA Induced Dyskinesia in Parkinsonian Rats: Effects of Doxycycline
ανά: G.C. Nascimento, κ.ά.
Έκδοση: (2023-03-01)

Dopaminergic-like neurons derived from oral mucosa stem cells by developmental cues improve symptoms in the hemi-parkinsonian rat model.
ανά: Javier Ganz, κ.ά.
Έκδοση: (2014-01-01)

The Advances in Antipsychotics-Induced Dyskinesia Rodent Models: Benefits of Antioxidant Supplementation
ανά: Uros Velickovic, κ.ά.
Έκδοση: (2025-02-01)

ANTIEMETIC ACTIVITY OF NEUROKININ NK1 RECEPTOR ANTAGONISTS IS MEDIATED CENTRALLY IN THE FERRET
ανά: Gardner, C, κ.ά.
Έκδοση: (1994)

5-Hydroxy-tryptophan for the treatment of l-DOPA-induced dyskinesia in the rat Parkinson's disease model
ανά: Elisabetta Tronci, κ.ά.
Έκδοση: (2013-12-01)

Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonist–induced orofacial dyskinesia
ανά: Koki Nagaoka, κ.ά.
Έκδοση: (2021-05-01)

Denervation and repeated l-DOPA induce a coordinate expression of the transcription factor NGFI-B in striatal projection pathways in hemi-parkinsonian rats
ανά: Michel St-Hilaire, κ.ά.
Έκδοση: (2003-10-01)

POS-431 ALTERED REGULATION OF TRYPTOPHAN METABOLISM AND ARYL HYDROCARBON RECEPTOR DISTRIBUTION IN RODENT POLYCYSTIC KIDNEYS
ανά: S. Nagao, κ.ά.
Έκδοση: (2021-04-01)

A sequential methodology for integral evaluation of motor and non-motor behaviors in parkinsonian rodents
ανά: Luis O. Soto-Rojas, κ.ά.
Έκδοση: (2020-01-01)

Systemic administration of an mGluR5 antagonist, but not unilateral subthalamic lesion, counteracts l-DOPA-induced dyskinesias in a rodent model of Parkinson's disease
ανά: Giovanna Levandis, κ.ά.
Έκδοση: (2008-01-01)

Validation of a Precise Impactor in a Rodent Cervical Spinal Cord Injury Hemi-Contusion Model
ανά: Jose A. Castillo, κ.ά.
Έκδοση: (2024-11-01)

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
ανά: Jaenisch, Rudolf, κ.ά.
Έκδοση: (2014)

The neurokinin 1 (NK) receptor antagonist GR205171 reduces carrageenan-evoked Fos-like immunoreactivity in the rat lumbar spinal cord
ανά: Smith, E, κ.ά.
Έκδοση: (1997)

Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age
ανά: Margaret E. Caulfield, κ.ά.
Έκδοση: (2023-06-01)

Antinociceptive activity of NK1 receptor antagonists: non-specific effects of racemic RP67580.
ανά: Rupniak, N, κ.ά.
Έκδοση: (1993)

IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA
ανά: Vastert Sebastiaan J, κ.ά.
Έκδοση: (2012-11-01)

Hemi facial spasm
ανά: A. V. Ciurea, κ.ά.
Έκδοση: (2007-03-01)

Hemi orolingual angioedema
ανά: Khurana Dheeraj, κ.ά.
Έκδοση: (2008-01-01)