The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model

Background: Dyskinesia or abnormal involuntary movements (AIMs) are a disabling effect of chronic l-DOPA administration and consequent pulsatile stimulation of dopamine receptors. This abnormal activation causes maladaptive changes including upregulation of FosB expression in dynorphin containing st...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkkit: Thornton, E, Hassall, M, Corrigan, F, Vink, R
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Elsevier 2014

Geahča maid