Deep brain stimulation for tremor resulting from acquired brain injury
OBJECTIVES: To evaluate the efficacy of deep brain stimulation (DBS) in the treatment of tremor resulting from acquired brain injury (ABI). METHODS: A series of eight consecutive patients with post-ABI tremor were treated with DBS of the ventro-oralis posterior (VOP)/zona incerta (ZI) region, and su...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
BMJ Publishing Group
2013
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| _version_ | 1797085496915001344 |
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| author | Sitsapesan, H Holland, P Oliphant, Z De Pennington, N Brittain, J Jenkinson, E Joint, C Aziz, T Green, A |
| author_facet | Sitsapesan, H Holland, P Oliphant, Z De Pennington, N Brittain, J Jenkinson, E Joint, C Aziz, T Green, A |
| author_sort | Sitsapesan, H |
| collection | OXFORD |
| description | OBJECTIVES: To evaluate the efficacy of deep brain stimulation (DBS) in the treatment of tremor resulting from acquired brain injury (ABI). METHODS: A series of eight consecutive patients with post-ABI tremor were treated with DBS of the ventro-oralis posterior (VOP)/zona incerta (ZI) region, and subsequently underwent blinded assessments using Bain's tremor severity scale. RESULTS: VOP/ZI DBS produced a mean reduction in tremor severity of 80.75% based on Bain's tremor severity scale, with significant reductions in all five component tremor subscores: rest, postural, kinetic, proximal and distal. No adverse neurological complications were reported, although one patient experienced exacerbation of pre-existing gait ataxia. CONCLUSION: VOP/ZI stimulation is demonstrated here to be an effective and safe approach for the treatment of post-ABI tremor in the largest series published at the time of writing. |
| first_indexed | 2024-03-07T02:09:41Z |
| format | Journal article |
| id | oxford-uuid:a030aeb9-354f-4cb7-85b3-38a3fde49988 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:09:41Z |
| publishDate | 2013 |
| publisher | BMJ Publishing Group |
| record_format | dspace |
| spelling | oxford-uuid:a030aeb9-354f-4cb7-85b3-38a3fde499882022-03-27T02:03:42ZDeep brain stimulation for tremor resulting from acquired brain injuryJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a030aeb9-354f-4cb7-85b3-38a3fde49988EnglishSymplectic Elements at OxfordBMJ Publishing Group2013Sitsapesan, HHolland, POliphant, ZDe Pennington, NBrittain, JJenkinson, EJoint, CAziz, TGreen, AOBJECTIVES: To evaluate the efficacy of deep brain stimulation (DBS) in the treatment of tremor resulting from acquired brain injury (ABI). METHODS: A series of eight consecutive patients with post-ABI tremor were treated with DBS of the ventro-oralis posterior (VOP)/zona incerta (ZI) region, and subsequently underwent blinded assessments using Bain's tremor severity scale. RESULTS: VOP/ZI DBS produced a mean reduction in tremor severity of 80.75% based on Bain's tremor severity scale, with significant reductions in all five component tremor subscores: rest, postural, kinetic, proximal and distal. No adverse neurological complications were reported, although one patient experienced exacerbation of pre-existing gait ataxia. CONCLUSION: VOP/ZI stimulation is demonstrated here to be an effective and safe approach for the treatment of post-ABI tremor in the largest series published at the time of writing. |
| spellingShingle | Sitsapesan, H Holland, P Oliphant, Z De Pennington, N Brittain, J Jenkinson, E Joint, C Aziz, T Green, A Deep brain stimulation for tremor resulting from acquired brain injury |
| title | Deep brain stimulation for tremor resulting from acquired brain injury |
| title_full | Deep brain stimulation for tremor resulting from acquired brain injury |
| title_fullStr | Deep brain stimulation for tremor resulting from acquired brain injury |
| title_full_unstemmed | Deep brain stimulation for tremor resulting from acquired brain injury |
| title_short | Deep brain stimulation for tremor resulting from acquired brain injury |
| title_sort | deep brain stimulation for tremor resulting from acquired brain injury |
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