A population genetics-phylogenetics approach to inferring natural selection in coding sequences.
Through an analysis of polymorphism within and divergence between species, we can hope to learn about the distribution of selective effects of mutations in the genome, changes in the fitness landscape that occur over time, and the location of sites involved in key adaptations that distinguish modern...
Main Authors: | Wilson, D, Hernandez, R, Andolfatto, P, Przeworski, M |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2011
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