Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction.

Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction.

Renal cell carcinoma (RCC) infiltrating lymphocytes (TILs) express killer cell immunoglobulinlike receptors (KIRs) that inhibit the antitumor CD8(+) T-cell lysis. In the present study, to better examine the functional consequences of KIR engagement on cytotoxic T lymphocyte (CTL)/tumor interaction,...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Guerra, N, Michel, F, Gati, A, Gaudin, C, Mishal, Z, Escudier, B, Acuto, O, Chouaib, S, Caignard, A
التنسيق:	Journal article
اللغة:	English
منشور في:	2002

مواد مشابهة

The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.
حسب: Hudrisier, D, وآخرون
منشور في: (1998)

CD28 affects the earliest signaling events generated by TCR engagement.
حسب: Tuosto, L, وآخرون
منشور في: (1998)

The efficiency of antigen recognition by CTL is determined by the frequency of serial TCR engagement.
حسب: Hudrisier, D, وآخرون
منشور في: (1998)

TCR usage by homocysteine-specific human CTL.
حسب: Chilvers, M, وآخرون
منشور في: (1998)

CD28-mediated co-stimulation: a quantitative support for TCR signalling.
حسب: Acuto, O, وآخرون
منشور في: (2003)

CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76?
حسب: Michel, F, وآخرون
منشور في: (2002)

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.
حسب: Michel, F, وآخرون
منشور في: (2001)

CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling.
حسب: Irles, C, وآخرون
منشور في: (2003)

Preclinical Studies of the Off-Target Reactivity of AFP158-Specific TCR Engineered T Cells
حسب: Lun Cai, وآخرون
منشور في: (2020-04-01)

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.
حسب: Michel, F, وآخرون
منشور في: (2000)

Both T cell receptor (TcR)-CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck.
حسب: Danielian, S, وآخرون
منشور في: (1992)

TCR repertoire characteristics predict clinical response to adoptive CTL therapy against nasopharyngeal carcinoma
حسب: Guoping Wang, وآخرون
منشور في: (2021-01-01)

Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production.
حسب: Kessler, B, وآخرون
منشور في: (1998)

CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens.
حسب: Marquez, M, وآخرون
منشور في: (2005)

TCR signal strength and T cell development
حسب: Gascoigne, N, وآخرون
منشور في: (2016)

The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers
حسب: Eline van Diest, وآخرون
منشور في: (2023-01-01)

Killer-Cell Inhibitory Receptors, CD158a/b, are Upregulated by Interleukin-2, but not Interferon-γ or Interleukin-4
حسب: Toshiaki Kogure, وآخرون
منشور في: (1999-01-01)

Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells
حسب: Karmel A Allison, وآخرون
منشور في: (2016-07-01)

Nanoscale kinetic segregation of TCR and CD45 in engaged microvilli facilitates early T cell activation
حسب: Yair Razvag, وآخرون
منشور في: (2018-02-01)

Growth rate-associated transcriptome reorganization in response to genomic, environmental, and evolutionary interruptions
حسب: Yuichiro Matsui, وآخرون
منشور في: (2023-03-01)

CTL priming by CD8(+) and CD8(-) dendritic cells in vivo.
حسب: Ruedl, C, وآخرون
منشور في: (1999)

LPA5 Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling
حسب: Divij Mathew, وآخرون
منشور في: (2019-05-01)

Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex
حسب: Caleb R. Glassman, وآخرون
منشور في: (2018-01-01)

TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling.
حسب: Abrahamsen, H, وآخرون
منشور في: (2004)

Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis
حسب: Emily Pollock, وآخرون
منشور في: (2014-10-01)

TCR V beta genes in man and mouse and the factors that shape the linkage pattern of immune receptor genes.
حسب: Acuto, O, وآخرون
منشور في: (1989)

CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection.
حسب: Borrow, P, وآخرون
منشور في: (1998)

Cognate MHC-TCR interaction leads to apoptosis of antigen-presenting cells.
حسب: Setterblad, N, وآخرون
منشور في: (2004)

T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component.
حسب: Brockmeyer, C, وآخرون
منشور في: (2011)

Biophysical Characterization of CD6—TCR/CD3 Interplay in T Cells
حسب: Marjolein B. M. Meddens, وآخرون
منشور في: (2018-10-01)

Presentación No. 158
حسب: El Editor
منشور في: (2021-11-01)

P158
حسب: N. Dementyeva, وآخرون
منشور في: (2015-11-01)

Dok-2 and Dok-1 adaptor proteins, two novel negative regulators of TCR signaling
حسب: Dong, S, وآخرون
منشور في: (2007)

Impact of secondary TCR engagement on the heterogeneity of pathogen-specific CD8+ T cell response during acute and chronic toxoplasmosis.
حسب: Lindsey A Shallberg, وآخرون
منشور في: (2022-06-01)

Distinct Features of Canine Non-conventional CD4−CD8α− Double-Negative TCRαβ+ vs. TCRγδ+ T Cells
حسب: Friederike V. Rabiger, وآخرون
منشور في: (2019-11-01)

T cell cross-reactivity and conformational changes during TCR engagement.
حسب: Lee, J, وآخرون
منشور في: (2004)

Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes
حسب: Minh Ngoc Duong, وآخرون
منشور في: (2019-11-01)

Modulation of CD103 expression on human colon carcinoma-specific CTL.
حسب: Ling, K, وآخرون
منشور في: (2007)

Role of Fyn in the rearrangement of tubulin cytoskeleton induced through TCR.
حسب: Martín-Cófreces, N, وآخرون
منشور في: (2006)

Counting CTL
حسب: François Laroussinie, وآخرون
منشور في: (2013-02-01)