Chromosomal location of human T-cell receptor gene Ti beta.
A complementary DNA probe corresponding to the beta-chain gene of Ti, the human T lymphocyte receptor, has been molecularly cloned. The chromosomal origin of the Ti beta gene was determined with the complementary DNA by screening a series of 12 cell hybrid (mouse X human) DNA's containing overl...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1984
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| _version_ | 1797085519703703552 |
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| author | Barker, P Ruddle, F Royer, H Acuto, O Reinherz, E |
| author_facet | Barker, P Ruddle, F Royer, H Acuto, O Reinherz, E |
| author_sort | Barker, P |
| collection | OXFORD |
| description | A complementary DNA probe corresponding to the beta-chain gene of Ti, the human T lymphocyte receptor, has been molecularly cloned. The chromosomal origin of the Ti beta gene was determined with the complementary DNA by screening a series of 12 cell hybrid (mouse X human) DNA's containing overlapping subsets of human chromosomes. DNA hybridization (Southern) experiments showed that the human Ti beta gene resides on chromosome 7 and is thus not linked to the immunoglobulin loci or to the major histocompatibility locus in humans. |
| first_indexed | 2024-03-07T02:09:55Z |
| format | Journal article |
| id | oxford-uuid:a04563ee-df86-4827-a397-0d4c290af4fc |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:09:55Z |
| publishDate | 1984 |
| record_format | dspace |
| spelling | oxford-uuid:a04563ee-df86-4827-a397-0d4c290af4fc2022-03-27T02:04:16ZChromosomal location of human T-cell receptor gene Ti beta.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a04563ee-df86-4827-a397-0d4c290af4fcEnglishSymplectic Elements at Oxford1984Barker, PRuddle, FRoyer, HAcuto, OReinherz, EA complementary DNA probe corresponding to the beta-chain gene of Ti, the human T lymphocyte receptor, has been molecularly cloned. The chromosomal origin of the Ti beta gene was determined with the complementary DNA by screening a series of 12 cell hybrid (mouse X human) DNA's containing overlapping subsets of human chromosomes. DNA hybridization (Southern) experiments showed that the human Ti beta gene resides on chromosome 7 and is thus not linked to the immunoglobulin loci or to the major histocompatibility locus in humans. |
| spellingShingle | Barker, P Ruddle, F Royer, H Acuto, O Reinherz, E Chromosomal location of human T-cell receptor gene Ti beta. |
| title | Chromosomal location of human T-cell receptor gene Ti beta. |
| title_full | Chromosomal location of human T-cell receptor gene Ti beta. |
| title_fullStr | Chromosomal location of human T-cell receptor gene Ti beta. |
| title_full_unstemmed | Chromosomal location of human T-cell receptor gene Ti beta. |
| title_short | Chromosomal location of human T-cell receptor gene Ti beta. |
| title_sort | chromosomal location of human t cell receptor gene ti beta |
| work_keys_str_mv | AT barkerp chromosomallocationofhumantcellreceptorgenetibeta AT ruddlef chromosomallocationofhumantcellreceptorgenetibeta AT royerh chromosomallocationofhumantcellreceptorgenetibeta AT acutoo chromosomallocationofhumantcellreceptorgenetibeta AT reinherze chromosomallocationofhumantcellreceptorgenetibeta |