Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade

Eitemau Tebyg

• Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
  gan: White, G, et al.
  Cyhoeddwyd: (2011)
• Hydrodynamic gene delivery of CC chemokine binding Fc fusion proteins to target acute vascular inflammation in vivo.
  gan: McNeill, E, et al.
  Cyhoeddwyd: (2015)
• Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines
  gan: McNeill, E, et al.
  Cyhoeddwyd: (2010)
• Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
  gan: Bursill, C, et al.
  Cyhoeddwyd: (2006)
• A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
  gan: Bursill, C, et al.
  Cyhoeddwyd: (2005)