Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade

Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade

Detalhes bibliográficos
Principais autores:	White, G, McNeill, E, Channon, K, Greaves, D
Formato:	Conference item
Publicado em:	2010

Registros relacionados

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
por: White, G, et al.
Publicado em: (2011)

Hydrodynamic gene delivery of CC chemokine binding Fc fusion proteins to target acute vascular inflammation in vivo.
por: McNeill, E, et al.
Publicado em: (2015)

Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines
por: McNeill, E, et al.
Publicado em: (2010)

Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
por: Bursill, C, et al.
Publicado em: (2006)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
por: Bursill, C, et al.
Publicado em: (2005)

Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice
por: Bursill, C, et al.
Publicado em: (2004)

Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
por: Bursill, C, et al.
Publicado em: (2003)

Adenoviral-mediated delivery of a CC-chemokine inhibitor ('35K') attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
por: Bursill, C, et al.
Publicado em: (2004)

Adenoviral delivery of a Cc-chemokine inhibitor, "35k," reduces macrophage recruitment and atherosclerosis in Apoe knockout mice
por: Bursill, C, et al.
Publicado em: (2004)

Adenoviral mediated delivery of a CC chemokine (CK) inhibitor ("35K") attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
por: Bursill, C, et al.
Publicado em: (2004)

Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
por: McNeill, E, et al.
Publicado em: (2014)

Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition.
por: Bursill, C, et al.
Publicado em: (2009)

Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice.
por: Bursill, C, et al.
Publicado em: (2004)

Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo.
por: Bursill, C, et al.
Publicado em: (2003)

Broad spectrum adenoviral CC-chemokine blockade attenuates long term vein graft accelerated atherosclerosis in ApoE-knockout mice
por: Ali, Z, et al.
Publicado em: (2007)

Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain
por: Katarzyna Pawlik, et al.
Publicado em: (2021-11-01)

CC chemokine receptors and chronic inflammation--therapeutic opportunities and pharmacological challenges.
por: White, G, et al.
Publicado em: (2013)

Chemokines, chemokine receptors and atherosclerosis
por: John, A, et al.
Publicado em: (2005)

The Downstream Regulation of Chemokine Receptor Signalling: Implications for Atherosclerosis
por: Jyoti Patel, et al.
Publicado em: (2013-01-01)

Role of site-directed mutagenesis and adjuvants in the stability and potency of anthrax protective antigen
por: Mohammed Ali Dahhas, et al.
Publicado em: (2022-05-01)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.
por: Ali, Z, et al.
Publicado em: (2005)

The roles of CC chemokines in response to radiation
por: Lei Wang, et al.
Publicado em: (2022-04-01)

Adenoviral gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice
por: Ali, Z, et al.
Publicado em: (2004)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter.
por: Liddiard, K, et al.
Publicado em: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
por: Liddiard, K, et al.
Publicado em: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
por: Liddiard, K, et al.
Publicado em: (2006)

YIA5 RGS-1 Regulates Leukocyte Trafficking in Atherosclerosis and Aortic Aneurysm Formation through Chemokine Receptor Desensitisation.
por: Patel, J, et al.
Publicado em: (2014)

Site-Directed Mutagenesis by Fusion of Contiguous DNA Fragments
por: Sergio Carmona, et al.
Publicado em: (1999-03-01)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces macrophage recruitment and smooth muscle content in vein graft atherosclerosis in apolipoprotein E-knockout mice
por: Ali, Z, et al.
Publicado em: (2005)

Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8
por: Dawei Sun, et al.
Publicado em: (2023-12-01)

CC chemokines Modulate Immune responses in Pulmonary Hypertension
por: Qian Yan, et al.
Publicado em: (2024-09-01)

Role of CC-chemokine ligand 2 in gynecological cancer
por: Jia-Jia Zhang, et al.
Publicado em: (2022-11-01)

Fractalkine promotes human monocyte survival via a reduction in oxidative stress.
por: White, G, et al.
Publicado em: (2014)

CC chemokines and receptors in osteoarthritis: new insights and potential targets
por: Yuchen Zhang, et al.
Publicado em: (2023-07-01)

Fractalkine: one chemokine, many functions.
por: White, G, et al.
Publicado em: (2009)

Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade
por: Denis M. Schewe, et al.
Publicado em: (2024-02-01)

The role of chemokines in atherosclerosis: recent evidence from experimental models and population genetics.
por: Bursill, C, et al.
Publicado em: (2004)

CC chemokine receptor 7 promotes macrophage recruitment and induces M2-polarization through CC chemokine ligand 19&21 in oral squamous cell carcinoma
por: Wan-Hang Zhou, et al.
Publicado em: (2022-07-01)

Single cell transcriptomics reveals how hyperlipidaemia alters monocyte/macrophage differentiation at sites of inflammation
por: Purvis, G, et al.
Publicado em: (2020)

Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications.
por: McNeill, E, et al.
Publicado em: (2010)